CD25 / IL2RA (Activated Lymphocyte Marker) Antibody - With BSA and Azide | LM10262 | Leading Biology

商品分类：单克隆抗体

产品概述：Recognizes a protein of 55kDa, identified as CD25. It is expressed on activated T- and B-cells and activated monocytes/macrophages. With respect to lymphomas, CD25 is present on malignant cells of Hodgkin?s disease, HTLV-1+ adult T-cell leukemia, cutaneous T-cell lymphoma, and hair cell leukemia. Increased levels of soluble CD25 are observed in the leukemias/lymphomas and inflammatory/ autoimmune diseases. CD25 molecule alone appears to function as a low affinity receptor and associates with CD122 (IL-2R chain, p75) and CD132 (common chain) to form the high affinity IL-2 receptor complex. CD25 antibodies detect three epitope regions, A, B and C. This MAb recognizes the epitope B, which is located at residue 3-104 of CD25 and doe not block IL-2 binding to CD25.

来源：Mouse

参考文献：L.A. Rubin, et al, (1985) Hybidoma 4: 91-102. | B. Boutin, et al, (1989) Neuropediatrics 20: 202-206. | T.A. Waldmann, et al, (1989) Annu Rev Biochem 58: 875-911. | T.A. Waldmann, et al, (1995) Blood 86: 4063-4075. | Leukocyte Typing IV (W. Knapp, et al, eds.) Oxford University Press, Oxford, (1989) p. 403-40

特异性：Human

别名：Interleukin-2 receptor subunit alpha, IL-2 receptor subunit alpha, IL-2-RA, IL-2R subunit alpha, IL2-RA, TAC antigen, p55, CD25, IL2RA

简单描述：Mouse Monoclonal CD25 / IL2RA (Activated Lymphocyte Marker) Antibody - With BSA and Azide. Validated for use in IF, FC. Clone: IL2RA/423.

详情：FunctionReceptor for interleukin-2.Cellular_LocationMembrane; Single-pass type I membrane protein

生物商城：http://www.annoron.com

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企业 QQ：3212874516、3198592576

地 址：北京大兴经济技术开发区(亦庄)同济中路7号兴盛国际A栋4层