CD25 / IL2RA (Activated Lymphocyte Marker) Antibody - Without BSA and Azide | LM10265 | Leading Biology

商品分类：单克隆抗体

产品概述：Recognizes a protein of 55kDa, identified as CD25 (Workshop IV; Code A27). CD25 is expressed on activated T- and B-cells and activated monocytes/macrophages. With respect to lymphomas, CD25 is present on malignant cells of Hodgkinā€?s disease, HTLV-1+ adult T-cell leukemia, cutaneous T-cell lymphoma, and hair cell leukemia. Increased levels of soluble CD25 are observed in the leukemias/lymphomas and inflammatory/ autoimmune diseases. CD25 molecule alone appears to function as a low affinity receptor and associates with CD122 (IL-2R ?? ? chain, p75) and CD132 (common ?? ? chain) to form the high affinity IL-2 receptor complex. CD25 antibodies detect three epitope regions, A, B and C. This MAb recognizes the epitope B, which is located at residue 3-104 of CD25 and can effectively block IL-2 binding to CD25.

来源：Mouse

参考文献：Knapp W. et al. Leucocyte typing IV, p. 408- 411 and p. 1080, Oxford University Press, Oxford 1989

特异性：Human

别名：Interleukin-2 receptor subunit alpha, IL-2 receptor subunit alpha, IL-2-RA, IL-2R subunit alpha, IL2-RA, TAC antigen, p55, CD25, IL2RA

简单描述：Mouse Monoclonal CD25 / IL2RA (Activated Lymphocyte Marker) Antibody - Without BSA and Azide. Validated for use in IF, FC. Clone: 143-13.

详情：FunctionReceptor for interleukin-2.Cellular_LocationMembrane; Single-pass type I membrane protein

生物商城：http://www.annoron.com

办公电话：010-56256916

官方售后：400-965-8633

企业 QQ：3212874516、3198592576

地 址：北京大兴经济技术开发区(亦庄)同济中路7号兴盛国际A栋4层