CD138肝素硫酸酯蛋白聚糖
广州健仑生物科技有限公司
CD138(Syndecan-1)是跨膜硫酸乙酸肝素蛋白聚糖家族的成员,通过其硫酸乙酸肝素链共价结合多种胞外配体。CD138 是一种细胞粘附分子,具有促进细胞增殖,细胞与基质、细胞与细胞之间粘附等多种功能。CD138 在某些肿瘤的表达明显缺失,导致细胞丧失生长接触YZ的功能,使得瘤细胞大量增殖,并具极强的侵袭活性。CD138表达于正常淋巴细胞不同的分化阶段,如前 B细胞、未成熟 B 细胞和浆细胞,同时还表达于上皮细胞、胚胎间质细胞、血管平滑肌细胞、内皮细胞和神经细胞的基底面。
我司还提供其它进口或国产试剂盒:登革热、疟疾、流感、A链球菌、合胞病毒、腮病毒、乙脑、寨卡、黄热病、基孔肯雅热、克锥虫病、违禁品滥用、肺炎球菌、军团菌、化妆品检测、食品安全检测等试剂盒以及日本生研细菌分型诊断血清、德国SiFin诊断血清、丹麦SSI诊断血清等产品。
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【产品介绍】
细胞定位:细胞膜
克隆号:B-A38
同型:IgG1
适用组织:石蜡/冰冻
阳性对照:扁桃体
抗原修复:热修复(EDTA)
抗体孵育时间:30-60min
产品编号 | 抗体名称 | 克隆型别 |
|
OB028 | Calponin-1(肌动蛋白结合蛋白) | EP798Y |
OB029 | Calretinin (钙视网膜蛋白) | 2E7 |
OB030 | CR(Calretinin) (钙视网膜蛋白) | polyclonal |
OB031 | CAM5.2(低分子细胞角蛋白) | CAM5.2 |
OB032 | CD10(共同型急性淋巴细胞白血病抗原) | 56C6 |
OB033 | CD117(酪氨酸激酶生长因子受体蛋白) | YR145 |
OB034 | CD11c(整合素α链蛋白) | 5D11 |
OB035 | CD138(肝素硫酸酯蛋白聚糖) | B-A38 |
OB036 | CD13(细胞膜表面糖蛋白) | SP187 |
OB037 | CD14(单核细胞) | EPR3653 |
OB038 | CD15(粒细胞) | MMA |
OB039 | CD163(M130抗原) | MRQ-26 |
OB040 | CD19(B细胞、滤泡树突状细胞) | MRQ-36 |
OB041 | CD19(B细胞、滤泡树突状细胞) | EP169 |
CD138肝素硫酸酯蛋白聚糖
实验原理
有些细菌具有合成淀粉酶的能力,可以分泌胞外淀粉酶。淀粉酶可以使淀粉水解为麦芽糖和葡萄糖,淀粉水解后遇碘不再变蓝色。
细菌产生的脂肪酶能分解培养基中的脂肪生成甘油及脂肪酸。脂肪酸可以使培养基pH下降,可通过在油脂培养基中加入中性红做指示剂进行测试。中性红指示范围为pH6.8(红)~8.0(黄)。当细菌分解脂肪产生脂肪酸时,则菌落周围培养基中出现红色斑点。
某些细菌分泌蛋白酶分解明胶,产生小分子物质。如果细菌具有分解明胶的能力,则培养基可由原来固体状态变成液体状态。
牛乳中主要含有乳糖、酪蛋白等成分。细菌对牛乳的利用主要是指对乳糖及酪蛋白的分解和利用。牛乳中常加入石蕊作为酸碱指示剂和氧化还原指示剂。石蕊中性时呈淡紫色,酸性时呈红色,碱性时呈蓝色,还原时则部分或全部脱色。细菌对牛乳的利用可分三种情况:
(1)酸凝固作用:细菌发酵乳糖后,产生许多酸,使石蕊牛乳变红,当酸度很高时,可使牛乳凝固,此称为酸凝固。
(2)凝乳酶凝固作用:某些细菌能分泌凝乳酶,使牛乳中的酪蛋白凝固,这种凝固在中性环境中发生。通常这种细菌还具有水解蛋白质的能力,因而产生氨等碱性物质,使石蕊变蓝。
(3)胨化作用:酪蛋白被水解,使牛乳变成清亮透明的液体。胨化作用可以在酸性条件下或碱性条件下进行,一般石蕊色素被还原褪色。
我司还提供其它进口或国产试剂盒:登革热、疟疾、流感、A链球菌、合胞病毒、腮病毒、乙脑、寨卡、黄热病、基孔肯雅热、克锥虫病、违禁品滥用、肺炎球菌、军团菌、化妆品检测、食品安全检测等试剂盒以及日本生研细菌分型诊断血清、德国SiFin诊断血清、丹麦SSI诊断血清等产品。
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【公司名称】 广州健仑生物科技有限公司
【市场部】 杨永汉
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【腾讯 】
【公司地址】 广州清华科技园创新基地番禺石楼镇创启路63号二期2幢101-103室
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Experimental principle
Some bacteria have the ability to synthesize amylase, which can secrete extracellular amylase. Amylase can hydrolyze starch to maltose and glucose, and iodine no longer turns blue after hydrolysis of starch.
Bacteria produce lipase can decompose the fat in the medium to produce glycerol and fatty acids. Fatty acids reduce the pH of the medium and can be tested by adding neutral red as an indicator in fat medium. Neutral red indicates a range of pH6.8 (red) to 8.0 (yellow). When bacteria break down fat to produce fatty acids, red spots appear in the medium around the colonies.
Some bacteria secrete protease to decompose gelatin to produce small molecules. If bacteria have the ability to break down gelatin, the medium can change from the original solid state to a liquid state.
Milk mainly contains lactose, casein and other ingredients. The use of bacteria by milk mainly refers to the decomposition and utilization of lactose and casein. Milk often add litmus as an acid-base indicator and redox indicator. Litmus lavender when neutral, acidic red, alkaline when blue, restore some or all of the decolorization. Bacteria on the utilization of milk can be divided into three situations:
(1) acid coagulation: Bacteria ferment lactose, resulting in many acids, the litmus milk turns red, when the acidity is high, the milk can coagulate, this is called acid coagulation.
(2) Rennet coagulation: Some bacteria can secrete rennet to coagulate casein in milk, which occurs in a neutral environment. Often this bacterium also has the ability to hydrolyze proteins, thus producing alkaline substances such as ammonia, turning the litmus bluish.
(3) peptonization: casein is hydrolyzed, so that the milk into a clear and transparent liquid. Peptonization can be carried out under acidic conditions or under alkaline conditions, and the litmus pigment is generally reduced and discolored.