CA-125 卵巢癌抗原（鼠单克隆抗体）

CA-125 卵巢癌抗原（鼠单克隆抗体）

广州健仑生物科技有限公司

CA125是1981年由Bast等从上皮性卵巢癌抗原检测出可被单克隆抗体OC125结合的一种糖蛋白，来源于胚胎发育期体腔上皮，在正常卵巢组织中不存在，因此Z常见于上皮性卵巢肿瘤（浆液性肿瘤）患者的血清中，其诊断的敏感性较高，但特异性较差。黏液性卵巢肿瘤中不存在。80%的卵巢上皮性肿瘤患者血清CA125升高，但近半数的早期病例并不升高，故不单独用于卵巢上皮性癌的早期诊断。90%患者血清CA125与病程进展有关，故多用于病情检测和LX评估。95%的健康成年妇女CA125的水平≤40U/ml，若升高至正常值的2倍以上应引起重视。另外CA125也可见于结核性腹膜炎患者的血清检查中，且CA125水平呈数十倍升高，在卵巢癌术前应明确排除结核性腹膜炎可能。

我司还提供其它进口或国产试剂盒：登革热、疟疾、流感、A链球菌、合胞病毒、腮病毒、乙脑、寨卡、黄热病、基孔肯雅热、克锥虫病、违禁品滥用、肺炎球菌、军团菌、化妆品检测、食品安全检测等试剂盒以及日本生研细菌分型诊断血清、德国SiFin诊断血清、丹麦SSI诊断血清等产品。

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【产品介绍】

细胞定位：细胞浆/细胞膜

克隆号：OC125

同型：IgG1/k

适用组织：石蜡/冰冻

阳性对照：卵巢癌/子宫内膜癌

抗原修复：热修复（EDTA）

抗体孵育时间：30-60min

CA-125 卵巢癌抗原（鼠单克隆抗体）

抗原抗体反应性曲霉菌病
过敏体制者吸入大量含有曲霉孢子的尘埃，引起过敏性鼻炎、支气管哮喘，支气管炎或变性肺曲霉菌病。吸入后数小时出现喘息、咳嗽和咳痰，可伴发热。大多数患者3—4天缓解，如再吸入又复发上述症状，痰中可检出大量嗜酸性粒细胞和菌丝。培养见烟熏色曲霉菌生长，血嗜酸性粒细胞增多（>1.0×109/L），血清IgE>1000ng/ml。
全身性曲霉菌病
多见于原发性和继发性免疫缺陷者。曲霉菌多由肺部病灶进入血循环，播散至全身多个脏器。白血病、恶性淋巴瘤、肿瘤、慢性肺部疾患、长期适用抗生素和皮质激素等，是发生本病的诱因。其临床表现随所侵犯的脏器而异，临床上以发热、全身中毒症状和栓塞Z常见。累及信内膜、心肌或心包，引起化脓、坏死和肉芽肿，神经系统受累引起脑膜炎和脑脓肿。消化系统以及肝受累多见。
疾病病因
曲霉菌属丝状真菌，是一种常见的条件致病性真菌，引起人类疾病常见的有烟曲霉菌和黄曲霉菌。
曲霉菌广布自然界，存在土壤、空气、植物、野生或家禽动物及飞鸟的皮毛。也常见于农田、马棚、牛栏、谷仓等处。可寄生于正常人的皮肤和上呼吸道，为条件致病菌。一般正常人对曲霉菌有一定的抵抗力，不引起疾病。曲霉菌病大多为继发性，当机体抵抗力降低时，病原菌可经皮肤黏膜损伤处或吸入呼吸道，进而进入血液循环到其他组织或抗原抗体而致病。过敏体制者吸入曲霉菌孢子可触发IgE介导的变化反应而支气管痉挛。
病理生理
曲霉菌Z常侵犯支气管和肺，可侵犯鼻窦、外耳道、眼和皮肤，或抗原抗体行播散至全身各抗原抗体。病变早期为弥漫性浸润渗出性改变；晚期为坏死，化脓或肉芽肿形成。病灶内可找到大量菌丝。菌丝穿透血管可引起血管炎、血管周围炎、血栓形成等，血栓形成又使组织缺血、坏死。

我司还提供其它进口或国产试剂盒：登革热、疟疾、流感、A链球菌、合胞病毒、腮病毒、乙脑、寨卡、黄热病、基孔肯雅热、克锥虫病、违禁品滥用、肺炎球菌、军团菌、化妆品检测、食品安全检测等试剂盒以及日本生研细菌分型诊断血清、德国SiFin诊断血清、丹麦SSI诊断血清等产品。

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【公司名称】 广州健仑生物科技有限公司
【市场部】    杨永汉

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【腾讯  】 
【公司地址】 广州清华科技园创新基地番禺石楼镇创启路63号二期2幢101-103室

Antigen Antibody Reactivity Aspergillosis
People with allergies inhale large amounts of dust containing Aspergillus spores, causing allergic rhinitis, bronchial asthma, bronchitis, or degenerative lung aspergillosis. A few hours after inhaling wheezing, coughing and expectoration may be associated with fever. Most patients 3-4 days to ease, such as re-inhalation and relapse of the above symptoms, sputum can be found in a large number of eosinophils and hyphae. See culture of Aspergillus smithii, blood eosinophilia (> 1.0 × 109 / L) and serum IgE> 1000 ng / ml.
Systemic aspergillosis
More common in primary and secondary immune deficiency. Aspergillus into the blood circulation by the lung lesions, spread to multiple organs throughout the body. Leukemia, malignant lymphoma, cancer, chronic lung disease, long-term use of antibiotics and corticosteroids, is the cause of the disease. Its clinical manifestations vary with the organs of infringement, clinical fever, systemic symptoms and embolism most common. Endocardial involvement of the letter, myocardium or pericardium, causing purulent, necrotic and granulomatous, central nervous system involvement cause meningitis and brain abscess. Digestive system and liver involvement more common.
Etiology of the disease
Aspergillus filamentous fungus, is a common condition pathogenic fungi, caused by human diseases are common Aspergillus fumigatus and Aspergillus flavus.
Aspergillus Widely distributed in nature, there is the soil, air, plants, wild or poultry animals and birds fur. Also common in farmland, horse shed, bullpen, barns and other places. Can be parasitic on normal skin and upper respiratory tract, as a condition of pathogenic bacteria. Normal normal people have some resistance to Aspergillus, does not cause disease. Aspergillosis is mostly secondary, when the body resistance is reduced, the pathogen can be inhaled through the skin and mucosal injury or respiratory tract, and then into the blood circulation to other tissues or antigen-antibody and pathogenic. Allergic aspiration of aspergillus spores triggers IgE-mediated changes in response to bronchospasm.
Pathophysiology
Aspergillus most often violates the bronchi and lungs and can invade the sinuses, external auditory meatus, eyes and skin, or antigen-antibody lines spread to all body antigens. Early diffuse diffuse infiltration of exudative changes; advanced necrosis, suppuration or granuloma formation. A large number of mycelium can be found within the lesion. Hyphae penetrate the blood vessels can cause vasculitis, perivascular inflammation, thrombosis, thrombosis and tissue ischemia and necrosis.