C044 Cyclosporin C, EvoPure/环孢菌素C, EvoPure

Cyclosporin C, EvoPure/环孢菌素C, EvoPure
产品编号：C044 
产品规格：5mg

CAS Number	59787-61-0
Molecular Formula	C62H111N11O13
Molecular Weight	1218.6 g/mol
Form	Powder
Appearance	Colorless prismatic needle
Purity Level	≥95.0%
Solubility	DMSO: Soluble Ethanol: Soluble
Source	Tolypocladium Inflatum
Water Content (Karl Fisher)	3.0%
Boiling Point	1316.0 °C
Melting Point	152-155 °C
Flash Point	749.7 °C
Storage Conditions	-20 °C

Description
Cyclosporin is an immunosuppressive cyclic polypeptide drug commonly used post-transplant to prevent graft rejection from the cytotoxic effects of T-cells.
TOKU-E offers seven forms of cyclosporin: cyclosporin A,EvoPure?, cyclosporin B, EvoPure?, cyclosporin C, EvoPure?,cyclosporin D, EvoPure?, cyclosporin E, EvoPure?, cyclosporin H, EvoPure?, and cyclosporin L, EvoPure?. Cyclosporin is soluble in DMSO and ethyl alcohol. EvoPure? products are purified single antibiotic fractions, most >99% pure.
Mechanism
Cyclosporins bind to the intercellular lymphocyte protein called cyclophilin. Cyclosporine:cyclophilin complexes target calcineurin, a protein-phosphatase which activates T-cells and ultimately prevents T-cell maturation and cytotoxic damage.
Mammalian Biology Applications