DAP12 (TYROBP)，Rabbit Monoclonal Antibod_详细资料

产品信息

DAP12 (TYROBP)，Rabbit Monoclonal Antibod【反应特异性】Human【克隆 ID】EPR5173【用途】WB , ICC【抗原分子量】12kDa

DAP12 （TYROBP）
Rabbit Monoclonal Antibody

Cas 号：

分子式：

别名： TYROBP antibody, DAP12 antibody, KARAP antibody, PLOSL antibody, TYRO protein tyrosine kinase-binding protein antibody, DNAX-activation protein 12 antibody, Killer-activating receptor-associated protein antibody

订货信息：

货号品名规格包装单价货期订购

DAP12 （TYROBP） 100ul 询价现货订购

性状：
【反应特异性】Human
【克隆 ID】EPR5173
DAP12 （TYROBP），Rabbit Monoclonal Antibod

【用途】WB , ICC
【抗原分子量】12kDa

质量标准： 【产品介绍】DAP12 is a transmembrane signaling
polypeptide which contains an immunoreceptor
tyrosine-based activation motif （ITAM） in its
cytoplasmic domain. It may associate with the
killer-cell inhibitory receptor （KIR） family of
membrane glycoproteins and may act as an activating
signal transduction element. DAP12 may bind zeta-chain
（TCR） associated protein kinase 70kDa （ZAP-70） and
spleen tyrosine kinase （SYK） and play a role in
signal transduction, bone modeling, brain myelination,
and inflammation. Mutations within this protein have
been associated with polycystic
lipomembranous osteodysplasia with
sclerosing leukoencephalopathy （PLOSL）, also known
as Nasu-Hakola disease. Its putative receptor,
triggering receptor expressed on myeloid cells 2
（TREM2）, also causes PLOSL （1）.

DAP12 （TYROBP），Rabbit Monoclonal Antibod
Recommended Applications

WB, ICC
Applications and Recommended Dilution Factors

WB: 1:1,000 - 10,000
ICC: 1:250 - 500
Species Reactivity *

Human

*Species cross-reactivity is based on WB analysis.

DAP12 （TYROBP），Rabbit Monoclonal Antibod

Products Data

Western blot analysis on （A） peripheral blood
leukocytes, （B） human placenta, and （C） peripheral
blood mononuclear cell lysates using anti-DAP12
RabMAb （cat. #5168-1）.

Specificity

A synthetic peptide corresponding to residues in human
DAP12 was used as an immunogen.

贮存：
DAP12 （TYROBP），Rabbit Monoclonal Antibod

Storage Condition and Buffer

Store at -20 °C. Antibody buffer, 0.01% sodium azide,
50% Glycerol and 0.05% BSA. Stable for 12 months from date
of receipt

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DAP12 (TYROBP)，Rabbit Monoclonal Antibod

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货号	品名	规格	包装	单价	货期	订购
	DAP12 （TYROBP）		100ul	询价	现货	订购