B7-H2 (ICOSLG)，Rabbit Monoclonal Antibod_详细资料

产品信息

B7-H2 (ICOSLG)，Rabbit Monoclonal Antibod【反应特异性】Human【克隆 ID】EPR6071【用途】WB , ICC【抗原分子量】63 - 72kDa

B7-H2 （ICOSLG）
Rabbit Monoclonal Antibody

Cas 号：

分子式：

别名： ICOSLG antibody, B7-H2 antibody, B7H2 antibody, B7RP-1 antibody, B7RP1 antibody, CD275 antibody, GL50 antibody, ICOS-L antibody, ICOSL antibody, KIAA0653 antibody, LICOS antibody, ICOS ligand antibody, B7-like protein Gl50 antibody, B7-related protein 1 a

订货信息：

货号品名规格包装单价货期订购

B7-H2 （ICOSLG） 100ul 询价现货订购

性状：
【反应特异性】Human
【克隆 ID】EPR6071
B7-H2 （ICOSLG），Rabbit Monoclonal Antibod

【用途】WB , ICC
【抗原分子量】63 - 72kDa

质量标准： 【产品介绍】B7-H2, or Inducible costimulator ligand
（ICOSL）, is a member of the Ig superfamily and belongs
to the B7 family of costimulatory molecules. It
specifically binds to ICOS, but not to other T
cell costimulatory molecules such as CD28 and
CTLA-4. B7-H2-ICOS interaction appears to be very
important in the expansion of activated T cells
and late-phase immune responses （1）. B7-H2 enhances
the proliferation of both CD4 and CD8 T cells, the
secretion of Th1- and/or Th2-type cytokines, and
the expression of CD154 （CD40 ligand） on T cells （2）. It
is expressed constitutively on B lymphocytes and at
low levels on monocytes （3）. Furthermore,
B7-H2-ICOS interaction induces IL-10 production, which
plays an important role in reducing immune responses （4）.

B7-H2 （ICOSLG），Rabbit Monoclonal Antibod
Recommended Applications

WB, ICC
Applications and Recommended Dilution Factors

WB: 1:1,000 - 10,000
ICC: 1:50 - 100
Species Reactivity *

B7-H2 （ICOSLG），Rabbit Monoclonal Antibod

Human

*Species cross-reactivity is based on WB analysis.

Products Data
Western blot analysis on （A） HL-60, （B） HuT78, （C）
HUVEC treated with TNF-alpha, and （D） HUVEC cell
lysates using anti-B7-H2 RabMAb （cat. #5329-1）.

B7-H2 （ICOSLG），Rabbit Monoclonal Antibod

Specificity

A synthetic peptide corresponding to residues in
the intracellular domain of human B7-H2 was used as
an immunogen.

贮存： Storage Condition and Buffer

B7-H2 （ICOSLG），Rabbit Monoclonal Antibod

Store at -20 °C. Antibody buffer, 0.01% sodium azide,
50% Glycerol and 0.05% BSA. Stable for 12 months from date
of receipt

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