eIF-3E (EIF3E)，Rabbit Monoclonal Antibod_详细资料

产品信息

eIF-3E (EIF3E)，Rabbit Monoclonal Antibod【反应特异性】Human , Mouse , Rat【克隆 ID】EPR6877【用途】WB , ICC【抗原分子量】48kDa

eIF-3E （EIF3E）
Rabbit Monoclonal Antibody

Cas 号：

分子式：

别名： EIF3E antibody, EIF3-P48 antibody, EIF3S6 antibody, INT6 antibody, eIF3-p46 antibody, Eukaryotic translation initiation factor 3 subunit E antibody, Eukaryotic translation initiation factor 3 subunit 6 antibody, Viral integration site protein INT-6 homolo

订货信息：

货号品名规格包装单价货期订购

eIF-3E （EIF3E） 100ul 询价现货订购

性状：
【反应特异性】Human , Mouse , Rat
【克隆 ID】EPR6877
eIF-3E （EIF3E），Rabbit Monoclonal Antibod

【用途】WB , ICC
【抗原分子量】48kDa

质量标准： 【产品介绍】eIF-3E is the p48 subunit of the
translational initiation factor eIF3. It forms a
multi-factor complex with eIF1, eIF5, and the
eIF2-GTP-Met-tRNA ternary complex that binds to the
40S ribosomal subunit to form the 43S preinitiation
complex （PIC）. eIF-3E also prevents the premature joining
of the 60S ribosomal subunit until the start codon
is recognized. In addition, eIF-3E plays a role
in recruiting eIF4G-associated mRNAs to the 43S PIC to
form the 48S PIC and initiate mRNA scanning （1）. It
is required for nonsense-mediated mRNA decay （NMD） and
acts in conjunction with UPF2 to divert mRNAs
from translation to the NMD pathway. eIF-3E also
interacts with MCM7 and EPAS1 and regulate the
proteasome-mediated degradation of these proteins （2）.

eIF-3E （EIF3E），Rabbit Monoclonal Antibod
Recommended Applications

WB, ICC
Applications and Recommended Dilution Factors

WB: 1:1,000 - 10,000
ICC: 1:100 - 250
Species Reactivity *

eIF-3E （EIF3E），Rabbit Monoclonal Antibod

Human, Mouse, Rat

*Species cross-reactivity is based on WB analysis.

Products Data

eIF-3E （EIF3E），Rabbit Monoclonal Antibod

Western blot analysis on （A） Jurkat, （B） 293T,
（C） BxPC-3, （D） A431, （E） Saos-2, （F） HepG2, and （G）
NIH/3T3 cell lysates using anti-eIF-3E RabMAb （cat. #5387-1）.

Specificity

A synthetic peptide corresponding to residues in
human eIF-3E was used as an immunogen.

贮存： Storage Condition and Buffer

eIF-3E （EIF3E），Rabbit Monoclonal Antibod

Store at -20 °C. Antibody buffer, 0.01% sodium azide,
50% Glycerol and 0.05% BSA. Stable for 12 months from date
of receipt

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