DDIT4 / REDD-1，Rabbit Monoclonal Antibod_详细资料

产品信息

DDIT4 / REDD-1，Rabbit Monoclonal Antibod【反应特异性】Human , Mouse , Rat【克隆 ID】EPR4037(2)【用途】WB , ICC【抗原分子量】35kDa

DDIT4 / REDD-1
Rabbit Monoclonal Antibody

Cas 号：

分子式：

别名： DDIT4 antibody, Dig2 antibody, FLJ20500 antibody, REDD-1 antibody, REDD1 antibody, RP11-442H21.1 antibody, RTP801 antibody, DNA damage-inducible transcript 4 protein antibody, HIF-1 responsive protein RTP801 antibody, Protein regulated in development and

订货信息：

货号品名规格包装单价货期订购

DDIT4 / REDD-1 100ul 询价现货订购

性状：
【反应特异性】Human , Mouse , Rat
【克隆 ID】EPR4037（2）
DDIT4 / REDD-1，Rabbit Monoclonal Antibod

【用途】WB , ICC
【抗原分子量】35kDa

质量标准： 【产品介绍】DDIT4 / REDD-1 is a transcriptional target
of p53 induced following DNA damage. It functions in
the regulation of reactive oxygen species （ROS）, which
is involved in p63-mediated regulation of
epithelial differentiation （1）. DDIT4 / REDD-1 inhibits
mTOR kinase activity in non-muscle and muscle
cells downstream of Akt/PKB and upstream of TSC2. As
a stress responsive negative regulator of mTOR signaling,
it is implicated in controlling skeletal muscle size
（2）. Studies show either a pro- or an anti-apoptotic
role during the stress response, depending on the
cell context （3）. Furthermore, DDIT4 / REDD-1 is
essential for hypoxia regulation of TORC1 activity （4）.

DDIT4 / REDD-1，Rabbit Monoclonal Antibod
Recommended Applications

WB, ICC
Applications and Recommended Dilution Factors

WB: 1:1,000 - 10,000
ICC: 1:100 - 250
Species Reactivity *

Human, Mouse, Rat

DDIT4 / REDD-1，Rabbit Monoclonal Antibod

*Species cross-reactivity is based on WB analysis.

Products Data

Western blot analysis on （A） Jurkat, （B） 293T, and
（C） K562 cell lysates using anti-DDIT4 / REDD-1 RabMAb
（cat. #5144-1）.

DDIT4 / REDD-1，Rabbit Monoclonal Antibod

Specificity

A synthetic peptide corresponding to residues in human
DDIT4 / REDD-1 was used as an immunogen.

贮存： Storage Condition and Buffer

DDIT4 / REDD-1，Rabbit Monoclonal Antibod

Store at -20 °C. Antibody buffer, 0.01% sodium azide,
50% Glycerol and 0.05% BSA. Stable for 12 months from date
of receipt

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DDIT4 / REDD-1，Rabbit Monoclonal Antibod

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货号	品名	规格	包装	单价	货期	订购
	DDIT4 / REDD-1		100ul	询价	现货	订购